1. Liu AP, ..., Stephanopoulos N, Chaudhuri O The living interface between synthetic biology and biomaterials design, Nature Materials (2022).  Article Link 
  2. Gupta VK and Chaudhuri O Mechanical regulation of cell-cycle progression and division, Trends in Cell Biology (2022).  Article Link 
  3. Indana D, Agarwal P, Bhutani N, Chaudhuri O Viscoelasticity and Adhesion Signaling in Biomaterials Control Human Pluripotent Stem Cell Morphogenesis in 3D Culture, Advanced Materials (2021).  Article Link 
  4. Slater B, Li J, Indana D, Xie Y, Chaudhuri O, Kim T Transient mechanical interactions between cells and viscoelastic extracellular matrix, Soft Matter (2021).  Article Link 
  5. Gupta VK, Nam S, Yim D, Camuglia J, Martin JL, Sanders EN, O'Brien LE, Martin AC, Kim T, Chaudhuri O, The nature of cell division forces in epithelial monolayers, Journal of Cell Biology (2021).  Article Link 
  6. Pokki J, Zisi I, Schulman E, Indana D, Chaudhuri O, Magnetic probe-based microrheology reveals local softening and stiffening of 3D collagen matrices by fibroblasts, Biomedical Microdevices (2021).  Article Link 
  7. Charbonier F, Indana D, Chaudhuri O, Tuning Viscoelasticity in Alginate Hydrogels for 3D Cell Culture Studies, Current Protocols (2021).  Article Link 
  8. Indana D, Chaudhuri O, Tumor Biology: Cells under pressure, eLife (2021).  Article Link 
  9. Adebowale K, Gong Z, Hou JC, Wisdom KM, Garbett D, Lee H, Nam S, Meyer T, Odde DJ, Shenoy VB, Chaudhuri O, Enhanced substrate stress relaxation promotes filopodia-mediated cell migration, Nature Materials (2021).  Article Link   Stanford Engineering news 
  10. Agarwal P, Lee H, Smeriglio P, Grandi F, Goodman S, Chaudhuri O, Bhutani N A dysfunctional TRPV4 - GSK3b pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity, Nature Biomedical Engineering (2021).  Article Link 
  11. Lee H, Alisafaei F, Adebawale K, Chang J, Shenoy VB, Chaudhuri O The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments, Science Advances (2021).  Article Link 
  12. Lee JY, Chaudhuri O Modeling the tumor immune microenvironment for drug discovery using 3D culture, APL Bioengineering (2021).  Article Link 
  13. Stowers R, Chaudhuri O Epigenetic regulation of mechanotransduction, Nature Biomedical Engineering (2021).  Article Link 
  14. Nam S, Lin Y, Kim T, Chaudhuri O Cellular pushing forces during mitosis drive mitotic elongation in collagen gels, Advanced Science (2021).  Article Link 
  15. Chaudhuri O, Cooper-White JJ, Janmey PA, Mooney DJ, Shenoy VB Effects of extracellular matrix viscoelasticity on cellular behaviour, Nature (2020).  Article Link 
  16. Chang J, Pang EM, Adebowale K, Wisdom KM, Chaudhuri O Increased stiffness inhibits invadopodia formation and cell migration in 3D, Biophysical Journal (2020).  Article Link 
  17. Lee JY, Dominguez AA, Nam S, Stowers RS, Qi LS, Chaudhuri O Identification of cell context-dependent YAP-associated proteins reveals b1 and b4 integrin mediate YAP translocation independently of cell spreading, Scientific Reports (2019).  Article Link 
  18. Nam S, Gupta VK, Lee H, Lee JY, Wisdom KM, Varma S, Flaum EM, Davis C, West RB, Chaudhuri O Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis, Science Advances (2019).  Article Link 
  19. Chang J and Chaudhuri O Beyond proteases: Basement membrane mechanics and cancer invasion, Journal of Cell Biology (2019).  Article Link 
  20. Stowers RS, Israeli J, Gruber JJ, Chang J, Nam S, Rabiee A, M Teruel, Snyder MP, Kundaje A, Chaudhuri O Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility, Nature Biomedical Engineering (2019).  Article Link   Stanford Engineering news 
  21. Wisdom KM, Indana D, Chou PE, Desai R, Kim T, Chaudhuri O, Covalent cross-linking of basement membrane-like matrices physically restricts invasive protrusions in breast cancer cells, Matrix Biology (2019).  Pubmed link 
  22. Chen Y, Nam S, Chaudhuri O, Huang HC, The evolution of spindles and their mechanical implications for cancer metastasis, Cell Cycle (2019).  Article Link 
  23. Lee JY, Chang J, Dominguez AA, Chang J, Nam S, Lee H, Varma S, Qi LS, West RB and Chaudhuri O, YAP-independent mechanotransduction drives breast cancer progression, Nature Communications, 10, 1848 (2019).  Article Link 
  24. Nam S, Stowers R, Lou J, Xia Y, and Chaudhuri O, Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies, Biomaterials 200: 15 - 24 (2019).  Article Link 
  25. Lee H, Stowers R, and Chaudhuri O, Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments, Nature Communications, 10, 529 (2019).  Article Link 
  26. Wisdom KM, Adebowale K, Chang J, Lee JY, Nam S, Desai R, Rossen NS, Rafat M, West RB, Hodgson L, and Chaudhuri O, Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments, Nature Communications, 9, 4144 (2018).  Article Link   Stanford news 
  27. Nam S and Chaudhuri O, Mitotic cells generate protrusive extracellular forces to divide in three-dimensional microenvironments, Nature Physics, 14, 621-628 (2018).  Article Link   Stanford Engineering news 
  28. Lou J*, Stowers R*, Nam S, Xia Y and Chaudhuri O, Stress Relaxing Hyaluronic Acid-Collagen Hydrogels Promote Cell Spreading, Fiber Remodeling, and Focal Adhesion Formation in 3D Cell Culture, Biomaterials 154:213-222 (2017).  PubMed Link 
  29. Lee H, Gu L, Mooney DJ, Levenston ME, and Chaudhuri O, Mechanical confinement regulates cartilage matrix formation by chondrocytes, Nature Materials 16(12), 1243 (2017).  Article Link 
  30. Wisdom KM and Chaudhuri O, 3D cell culture in interpenetrating networks of alginate and rBM matrix, Methods Molecular Biology 1612:29-37 (2017).  PubMed Link 
  31. Chaudhuri O Viscoelastic Hydrogels for 3D Cell Culture , Biomaterials Science 5(8):1480-1490 (2017).  PubMed Link 
  32. Lee JY, Chaudhuri O, Regulation of breast cancer progression by extracellular matrix mechanics: insights from 3D culture models, ACS Biomaterials Science and Engineering (2017).  Article Link 
  33. Liu A, Chaudhuri O, Parekh SH New Advances in Probing Cell-Extracellular Matrix Interactions, Integrative Biology (2017).  PubMed Link 
  34. Nam S, Lee J, Brownfield DG, Chaudhuri O, Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells, Biophysical Journal (2016).  PubMed Link 
  35. Nam S, Hu KH, Butte MJ, Chaudhuri O, Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels, Proceedings of the National Academy of Sciences (2016).  PubMed Link   PubMed Link 
  36. Miserez A, Weaver JC, Chaudhuri O, Biological materials and molecular biomimetics - filling up the empty soft materials space for tissue engineering applications, Journal Materials Chemistry B , 3, 13 - 24 (2015).  Link 


  1. Chiu P, Lee H, Dalal HR, Koyano T, Nguyen T, Connolly A, Chaudhuri O, Fischbein MP Relative Strain is a Novel Predictor of Aneurysmal Degeneration of the Thoracic Aorta: an Ex-Vivo Mechanical Study, JVS: Vascular Science (2021).  Article Link 
  2. Gong Z, Wisdom KM, McEvoy E, Chang J, Adebowale K, Price CC, Chaudhuri O, Shenoy VB, Recursive feedback between matrix dissipation and chemo-mechanical signaling drives oscillatory growth of cancer cell invadopodia, Cell Reports (2021).  PubMed Link 
  3. Lou J, Liu F, Chaudhuri O, Heilshorn S, Xia Y, Dynamic Hyaluronan Hydrogels with Temporally Modulated High Injectability and Stability Using a Biocompatible Catalyst, Advanced Materials 1705215 (2018).  PubMed Link 
  4. Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, and Shenoy VB, Matching Material and Cellular Timescales Maximizes Cell Spreading on Viscoelastic Substrates, Proceedings of National Academy of Sciences of the USA 115(12):E2686-E2695 (2018).  PubMed Link 
  5. Ban E, Franklin JM, Nam S, Smith L, Wang H, Wells RG, Chaudhuri O, Liphardt JT, Shenoy VB, Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces, Biophysical Journal 114(2) 450:461, 2018.  PubMed link 
  6. Madl CM, LeSavage BL, Dewi RE, Dinh CB, Stowers RS, Khariton M, Lampe KJ, Nguyen D, Chaudhuri O, Enejder A, Heilshorn SC, Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling, Nature Materials 16(12) 1233:1242, 2017.  Article Link 
  7. Ayala P, Dai E, Hawes M, Liu L, Chaudhuri O, Haller CA, Mooney DJ, Chaikof EL, Evaluation of a bioengineered construct for tissue engineering applications, Journal of Biomaterials Research B: Applied Biomaterials 2017.  PubMed Link 
  8. Branco da Cunha C, Klumpers DD, Koshy ST, Weaver JC, Chaudhuri O, Seruca R, Carneiro F, Granja PL, Mooney DJ, CD44 alternative splicing in gastric cancer cells is regulated by culture dimensionality and matrix stiffness, Biomaterials (2016).  PubMed Link 


  1. Chaudhuri O*, Guo L*, Klumpers DD, Darnell M, Bencherif S, Weaver J, Huebsch N, Mooney DJ, Hydrogels with tunable stress relaxation regulate stem cell fate and activity, Nature Materials (2015).  PubMed Link 
  2. Chaudhuri O*, Guo L*, Klumpers DD, Darnell M, Bencherif S, Weaver J, Huebsch N, Mooney DJ, Substrate stress relaxation regulates cell spreading, Nature Communications 6:6364 (2015).  PubMed Link 
  3. Huebsch N, Lippens E, Lee K, Mehta M, Koshy ST, Darnell MC, Desai RM, Madl CM, Xu M, Zhao X, Chaudhuri O, Verbeke C, Kim WS, Alim K, Mammoto A, Ingber DE, Duda GN, Mooney DJ, Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation, Nature Materials (2015).  PubMed Link 
  4. Ayala P, Caves J, Dai E, Siraj L, Liu L, Chaudhuri O, Haller CA, Mooney DJ, Chaikof EL, Engineered composite fascia for stem cell therapy in tissue repair applications, Acta Biomaterialia S1742-7061(15)30056-8 (2015).  PubMed Link 
  5. Chaudhuri O, Koshy ST, Branco da Cunha C, Shin JW, Verbeke CS, Allison KH, Mooney DJ, Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium, Nature Materials ,13, 970 - 978 (2014).  PubMed Link 
  6. Branco da Cunha C, Klumpers DD, Li WA, Koshy ST, Weaver JC, Chaudhuri O, Granja PL, Mooney DJ. Influence of the stiffness of three-dimensional alginate/collagen-I interpenetrating networks on fibroblast biology, Biomaterials. 35(32):8927-36 (2014)  PubMed Link 
  7. Priddy LB, Chaudhuri O, Stevens HY, Krishnan L, Uhrig BA, Willett NJ, Guldberg RE., Oxidized alginate hydrogels for bone morphogenetic protein-2 delivery in long bone defects, Acta Biomaterialia pii: S1742-7061(14)00262-1 (2014)  PubMed Link 
  8. Sun JY, Zhao X, Illeperuma WRK, Chaudhuri O, O KH, Mooney DJ, Vlassak JJ, Suo Z, Highly stretchable and tough hydrogels , Nature 489, 133-136 (2012).  PubMed Link 
  9. Chaudhuri O and Mooney DJ, Stem-Cell differentiation: Anchoring cell-fate cues, Nature Materials 11, 568 - 569 (2012).  PubMed Link 
  10. Risca VI, Wang EB, Chaudhuri O, Chia JJ, Geissler PL, Fletcher DA, Actin filament curvature biases branching direction, Proceedings of National Academy of Sciences of the USA , 109, 8, 2913:2918 (2012).  PubMed Link 
  11. Lam WA*, Chaudhuri O*, Crow A, Webster KD, Li T, Kita A, Huang J, Fletcher DA, Mechanics and contraction dynamics of single platelets and implications for clot stiffening, Nature Materials 10, 61-66 (2011).  PubMed Link 
  12. Chaudhuri O, and Fletcher DA, Protrusive forces generated by dendritic actin networks during cell crawling, Chapter for Actin-Based Motility, part 3, 359 - 379 (2010).  PubMed Link 
  13. Chaudhuri O, Parekh SH, Lam WA, Fletcher DA, Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells, Nature Methods, 6, 383-387 (2009).  PubMed Link 
  14. Choy JL, Parekh SH, Chaudhuri O, Liu AP, Bustamante C, Footer MJ, Theriot JA, Fletcher DA, Differential force microscope for long time-scale biophysical measurements, Review of Scientific Instruments 78, (2007).  PubMed Link 
  15. Chaudhuri O*, Parekh SH*, Fletcher DA, Reversible stress softening of actin networks, Nature 445, 295 - 298 (2007).  PubMed Link 
  16. Parekh SH*, Chaudhuri O*, Theriot JA, Fletcher, DA, Loading history determines the velocity of actin-network growth, Nature Cell Biology 7, 1219 - 1223 (2005).  PubMed Link 

* indicates co-first authorship