ABOUT THE LAB
We are interested in elucidating the complex mechanical properties of cells and the extracellular matrix, and in turn, investigating how these mechanical properties and other mechanical cues play a role in important biological processes such as cancer progression, stem cell differentiation, or cell division. Our approach is to develop new force-measurement instrumentation and engineered biomaterials for 3D cell culture to provide new insight into these areas.
Joanna's Review' paper entitled "Regulation of breast cancer progression by extracellular matrix mechanics: insights from 3D culture models" has been published in ACS Biomater. Sci. Eng.!
Check out our recent review article entitled "New advances in probing cell-extracellular matrix interactions", published in Integrative Biology.
Sungmin's paper entitled "Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells" has been published in Biophysical Journal!