ABOUT THE LAB
We are interested in elucidating the complex mechanical properties of cells and the extracellular matrix, and in turn, investigating how these mechanical properties and other mechanical cues play a role in important biological processes such as cancer progression, stem cell differentiation, or cell division. Our approach is to develop new force-measurement instrumentation and engineered biomaterials for 3D cell culture to provide new insight into these areas.
January 31, 2019
Hong-pyo and Ryan's paper entitled "Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments" has been published in Nature Communications! Check it out here
February 1, 2019
Ester Schulman has joined the lab as a visiting student from Aalto University. Welcome!
October 8, 2018
Katrina's paper entitled "Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments" has been published in Nature Communications! Check it out here